2ZY was the name of a radio station broadcast by the British Broadcasting Company from Manchester, England, between 1922 and 1927. The station aired its first test transmission on 450 metres on May 17, 1922 and began regular broadcasting on November 15, 1922, just a day after sister station 2LO began daily programmes in London. On the same day, 5IT began in Birmingham and eight other stations opened in subsequent months across Britain. The frequency chosen for 2ZY was then 375 metres medium wave. The programmes were made and broadcast at first from the Metropolitan-Vickers electricity works in Old Trafford. The ornate iron water tower at the works was the site of the transmitter.
After the opening of the BBC National Programme in 1927, the local material put out by 2ZY and the others was known as the BBC Regional Programme and the 2ZY name was dropped. Both the National and Regional services were combined in 1939 to form the Home Service.